Against the odds : the story of AIDS drug development, politics, and profits /

Against the odds : the story of AIDS drug development, politics, and profits / Peter S. Arno and Karyn L. Feiden.

Against the Odds is the most important book yet written about the quest for a cure and treatments for AIDS. Peter Arno and Karyn Feiden cut through the complex issues to tell the tragic, inspiring story behind the scenes of the AIDS crisis--how a diverse group of extraordinary people banded together...

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Bibliographic Details
Main Author: Arno, Peter S., 1954-
Other Authors: Feiden, Karyn.
Format: Book
Language:English
Published: New York : HarperCollins, [1992]
Edition:First edition.
Subjects:
AIDS (Disease) > Government policy > United States.
AIDS (Disease) > Chemotherapy.
Drug development > Government policy > United States.
HIV/AIDS.
STDs.
Table of Contents:
  • 1. Unlikely Heroes
  • 2. A New Virus: The Search for Magic Bullets
  • 3. The FDA and the Public Interest
  • 4. The AZT Breakthrough
  • 5. Placebos and Profiteering
  • 6. The Rise of the AIDS Underground
  • 7. Activism, ACT UP, and Dextran Sulfate
  • 8. The Pentamidine Saga
  • 9. Loosening the Regulatory Leash
  • 10. Grassroots Trials Come of Age: Activists Seizing Control
  • 11. Business as Usual: The Patenting and Pricing of AZT
  • 12. On the Defensive: Pentamidine Profits and a Corporation Under Siege
  • 13. Absence of Vision: The Ganciclovir Scandal
  • 14. Parallel Track and the Promise of ddI
  • 15. Research on Trial: The Limits of the Government System
  • 16. AIDS and Women, Children, and Minorities
  • 17. The Illicit Compound Q Trials
  • 18. The ddI Milestone
  • 19. Crashing the Gates: Activists Enter the Drug Testing Sanctum
  • Appendix A: Milestones in AIDS Drug Development
  • Appendix B: How a Clinical Trial Is Designed
  • Appendix C: The Challenge to the AZT Patent.

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