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| 001 |
EBC938848 |
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MiAaPQ |
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m o d | |
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cr cn||||||||| |
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111025s2012 njua sb 001 0 eng d |
| 010 |
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|z 2011044253
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|z 9780470878279 (cloth)
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| 020 |
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|z 9781118274378 (e-book)
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|a (MiAaPQ)EBC938848
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|a (Au-PeEL)EBL938848
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|a (CaONFJC)MIL367371
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|a (OCoLC)802068199
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|a MiAaPQ
|c MiAaPQ
|d MiAaPQ
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4 |
|a RS100 .D78 2012
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| 245 |
0 |
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|a Drug repositioning
|h [electronic resource] :
|b bringing new life to shelved assets and existing drugs /
|c edited by Michael J. Barratt, Donald E. Frail.
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| 260 |
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|a Hoboken :
|b John Wiley & Sons,
|c c2012.
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| 300 |
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|a xx, 477 p. :
|b ill.
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| 504 |
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|a Includes bibliographical references and index.
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| 505 |
0 |
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|a Drug repositioning : the business case and current strategies to repurpose shelved candidates and marketed drugs / John Arrowsmith and Richard Harrison -- Opportunities and challenges associated with developing additional indications for clinical development candidates and marketed drugs / Donald Frail and Michael Barratt -- Clinical and operational considerations in repositioning marketed drugs and drug candidates / Damian O'Connell, David Sequeira, and Maria Miller -- Regulatory considerations and strategies for drug repositioning / Ken Phelps -- Computational and bioinformatic strategies for drug repositioning / Richard Mazzarella and Craig Webb -- Mining scientific and clinical databases to identify novel uses for existing drugs / Christos Andronis ... [et al.] -- Predicting the polypharmacology of drugs : identifying new uses through chemoinformatics, structural informatics and molecular modeling based approaches / Li Xie ... [et al.] -- Systematic phenotypic screening for novel synergistic combinations: a new paradigm for repositioning existing drugs / Margaret Lee -- Phenotypic in vivo screening to identify new, unpredicted indications for existing drugs and drug candidates / Michael Saporito, Christopher Lipinski, and Andrew Reaume -- Old drugs yield new discoveries : examples from the prodrug, chiral switch and site-selective deuteration strategies / Adam Morgan ... [et al.] -- Repurposing drugs for tropical diseases : case studies and open-source screening initiatives / Curtis Chong -- Drug repositioning efforts by non-profit foundations -- Business development strategies in the repositioning industry / Aris Persidis and Elizabeth Stark -- A case study in drug repositioning : Sosei / Akinori Mochizuki and Makiko Aoyama.
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| 506 |
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|a Access to electronic resources restricted to Simmons University students, faculty and staff.
|
| 533 |
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|a Electronic reproduction. Ann Arbor, MI : ProQuest, 2015. Available via World Wide Web. Access may be limited to ProQuest affiliated libraries.
|
| 650 |
|
0 |
|a Pharmaceutical industry
|x Economic aspects.
|
| 650 |
|
0 |
|a Drugs
|x Economic aspects.
|
| 655 |
|
4 |
|a Electronic books.
|
| 700 |
1 |
|
|a Barratt, Michael J.
|
| 700 |
1 |
|
|a Frail, Donald.
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| 710 |
2 |
|
|a ProQuest (Firm)
|
| 856 |
4 |
0 |
|u https://ebookcentral.proquest.com/lib/simmons-ebooks/detail.action?docID=938848
|y Access E-Book
|
| 999 |
f |
f |
|i 66e65419-235c-3526-bede-bcbc0cd7c5cc
|s 2b7aea98-1fac-11eb-99cd-4c044419675a
|
| 852 |
|
|
|b Online Resources
|h RS100 .D78 2012
|0 7e56d38e-d50f-39f6-ae21-beb1c13f6a66
|
