Notable people called Sissel include:
* Sissel Solbjørg Bjugn (1947–2011), a Norwegian poet and children's writer
* Sissel Birgitte Breie (born 1953), a Norwegian diplomat
* Sissel Buchholdt, née Brenne (born 1951), a Norwegian handball player
* Sissel Grottenberg (born 1956), a retired Norwegian long-distance runner
* Sissel Knutsen Hegdal (born 1965), a Norwegian politician for the Conservative Party
* Sissel Kyrkjebø (born 1969), also known as Sissel, Norwegian singer
* Sissel Lange-Nielsen, née Herlofson (born 1931), a Norwegian writer, literary critic, and journalist
* Sissel Lie (born 1942), a Norwegian novelist, translator, playwright and professor in Romance languages and literature at the University of Trondheim
* Sissel Benneche Osvold (born 1945), a Norwegian journalist
* Sissel Vera Pettersen (born 1977, a Norwegian jazz vocalist, saxophonist and composer
* Sissel Rønbeck (born 1950), a Norwegian politician for the Labour Party
* Sissel Sellæg (1928–2014), a Norwegian actress
* Sissel Tolaas, a contemporary Norwegian installation artist most widely known for her work with odours
