Bone Thugs-n-Harmony are the only group that has worked with renowned American rappers Tupac Shakur, the Notorious B.I.G., Eazy-E, and Big Pun while they were all still alive. About.com ranked them 12 on its list of the 25 Best Rap Groups of All Time, and MTV called them "the most melodic hip-hop group of all time".
Krayzie Bone and Wish Bone briefly stepped away from the group in April 2011 to work with their independent label The Life Entertainment. But would both soon return reuniting with the rest of the group. In August 2013 Layzie Bone announced that he also would briefly step away from the group to work more on his independent label Harmony Howse Entertainment. He too would also reunite with the rest of the group shortly after. In the same month, BTNH signed with eOne Music (formerly known as Koch Records), with whom they had previously partnered to release 2006's ''Thug Stories''.
