Rothstein "transformed organized crime from a thuggish activity by hoodlums into a big business run like a corporation", and gained notoriety as the person who first realized that Prohibition was a business opportunity, a means to enormous wealth, who "understood the truths of early 20th century capitalism (giving people what they want) and came to dominate them". His notoriety inspired several fictional characters based on his life, portrayed in contemporary and later short stories, novels, musical theater productions, television shows, and films, including the character Meyer Wolfsheim in ''The Great Gatsby''.
Rothstein refused to pay a large debt resulting from a fixed poker game and was murdered in 1928. His illegal empire was broken up and distributed among a number of other underworld organizations and led in part to the downfall of Tammany Hall and the rise of reformer Fiorello La Guardia. Ten years after his death, his brother declared Rothstein's estate was insolvent.
