Roddick was involved in activism and campaigning for environmental and social issues, including involvement with Greenpeace and ''The Big Issue''. In 1990, Roddick founded Children on the Edge, a charitable organisation which helps disadvantaged children in Eastern Europe, Africa and Asia. She believed that business should offer a form of moral leadership, being a more powerful force in society than religion or government.
In the late 1990s, she became involved in advocating for the Angola Three, African-American prisoners at the Louisiana State Penitentiary who had already been held in solitary confinement for decades. She helped raise international awareness and funds to aid in their appeals of flawed trials.
