*Don Mitchell (actor) (1943–2013), American actor best known for his role in the TV series ''Ironside''
*Don Mitchell (aircraft designer), designer of the Mitchell Nimbus, Mitchell U-2 Superwing and AmeriPlanes Mitchell Wing A-10
*Don Mitchell (geographer) (born 1961), professor of geography at the Maxwell School of Syracuse University
*Don Mitchell (politician) (born c. 1951), Canadian politician, mayor of Whitby
